OPC Supreme

Why do we need antioxidants?

Antioxidants are natural compounds found in some foods that help neutralize free radicals in our bodies. Free radicals are substances that occur naturally in our bodies that attack the fats, protein and the DNA in our cells, ultimately causing different types of diseases by accelerating the aging process. Therefore, antioxidants play an important role in our overall health.

Why do we choose Andorra’s OPC Supreme?

Andorra’s OPC Supreme contains 4 types natural’s most powerful antioxidants extract.

Grapeseed extract:

Grapeseed extract is an excellent source of specific polyphenol antioxidants called OPCs, which have been clinically proven to fight free radicals and provide many healthy-aging benefits. Grapeseed extract supports production and stability of collagen and elastin, the two proteins which are very important to connective tissue health.  Grapeseed extract also supports cardiovascular health and a healthy immune system.

All parts of red grapes contain some proanthocyanidins, including the juice, skins and seeds, and the highest source of small molecule and highly bioactive oligomeric proanthocyanidins (OPCs) are found in red grape seeds. Misleading marketers market their white grape products and lower quality red grape products as red grape seed extracts.  For the purpose of dietary supplements, only red grape seed extracts have the overwhelming science behind them.

Vitamin C:

Vitamin C is an essential nutrient for humans and certain other animal species. Vitamin C is a cofactor in at least eight enzymatic reactions, including several collagen synthesis reactions.  Ascorbate (a form of Vitamin C) may also act as an antioxidant against oxidative stress. It is required for a range of essential metabolic reactions in all animals and plants. Furthermore, it is made internally by almost all organisms but not humans. Humans absorb Vitamin C from the diet.   A major deficiency of vitamin c can cause the most severe symptoms of scurvy.

Andorra International’s Nature C is the new form of Vitamin C, clinically proven superior to standard vitamin c supplements.  It contains vitamin C-lipid metabolites for enhanced delivery, absorption and utilization throughout your body. Nature C also improves blood plasma and tissue retention of vitamin C.

Green Tea Extract:

A green tea extract is an herbal derivative from green tea leaves. Containing antioxidant ingredients – mainly green tea catechins (GTC) – green tea and its derivatives are sought-after amongst people who pursue good health. The Indian and Chinese have used the green tea for hundreds of years for a wide variety of health related functions. These cultures have used green tea to treat headaches, aching body parts to improve life expectancy and more.

Pine Bark Extract:

Pine bark extract is made from the bark of the maritime pine tree, which contains naturally occurring OPCs. Pine bark extract is used for its antioxidant properties and multiple anti-aging benefits, such as improving the hearts condition, providing joint support, skin care, eye and vision support, and to ameliorate the condition of chronic venous insufficiency (blood circulation).

Andorra’s OPC Supreme brings you:
•    Highest quality ingredients: All Natural, Non GMO
•    Maximum strength and science- based grapeseed extract formulation for optimal health
•    Made in the USA in and the production facility is FDA inspected and registered  as well to meet the stringent standards of US Pharmacopeia (USP) for quality, purity and potency.

OPC Supreme Supplement Ingredients:
OPC Supp Fact


  1. Araghi-Niknam M, Hosseini S, Larson D, Rohdewald P, Watson RR. Pine bark extract reduces platelet aggregation. Integr Med. 2000;2:73-77.
  2. Summary of data for chemical selection: oligomeric proanthocyanidins from grape seeds and pine bark. National Toxicology Program Web site. Accessed athttp://ntp.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPdf/GrapeSeeds_PineBark.pdf on June 6, 2008.
  3. Devaraj S, Vega-López S, Kaul N, et al. Supplementation with a pine bark extract rich in polyphenols increase plasma antioxidant capacity and alters the plasma lipoprotein profile.Lipids. 2002;37:931-934.
  4. Downs AM, Sansom JE. Colophony allergy: a review.Contact Dermatitis.1999;41:305-310.
  5. Fetrow CW, Avila JR.Professional’s Handbook of Complementary & Alternative Medicines. Springhouse, PA: Springhouse Corp; 1999.
  6. Pine Bark. PDRhealth Web site. Accessed at www.pdrhealth.com/drugs/altmed/altmed-mono.aspx?contentFileName=ame0425.xml&contentName=Pine+Bark+ on June 6, 2008.
  7. Kushi LH, Doyle C, McCullough M, et al; American Cancer Society 2010 Nutrition and Physical Activity Guidelines Advisory Committee. American Cancer Society guidelines on Nutrition and Physical Activity for cancer prevention: reducing the risk of cancer with healthy food choices and physical activity.CA Cancer J Clin. 2012;62:30-67.
  8. McEvoy CT, Schilling D, Clay N, Jackson K, Go MD, Spitale P, Bunten C, Leiva M, Gonzales D, Hollister-Smith J, Durand M, Frei B, Buist AS, Peters D, Morris CD, Spindel ER. Vitamin Csupplementation for pregnant smoking women and pulmonary function in their newborn infants: a randomized clinical trial. JAMA. 2014 May;311(20):2074-82. doi: 10.1001/jama.2014.5217.
  9. Jubiz W, Ramirez M. Effect ofvitamin C on the absorption of levothyroxine in patients with hypothyroidism and gastritis. J Clin Endocrinol Metab. 2014 Jun;99(6):E1031-4. doi: 10.1210/jc.2013-4360. Epub 2014 Mar 6.
  10. Mazloom Z, Ekramzadeh M, Hejazi N. Pak.Efficacy of supplementary vitamins C and E on anxiety, depression and stress in type 2 diabetic patients: a randomized, single-blind, placebo-controlled trial. J Biol Sci. 2013 Nov 15;16(22):1597-600.
  11. Hong YH, Jung EY, Shin KS, Yu KW, Chang UJ, Suh HJ. Tannase-convertedgreen tea catechins and their anti-wrinkle activity in humans. J Cosmet Dermatol. 2013 Jun;12(2):137-43. doi: 10.1111/jocd.12038.
  12. Basu A, Betts NM, Mulugeta A, Tong C, Newman E, Lyons TJ. Greentea supplementation increases glutathione and plasma antioxidant capacity in adults with the metabolic syndrome. Nutr Res. 2013 Mar;33(3):180-7. doi: 10.1016/j.nutres.2012.12.010. Epub 2013 Jan 30.
  13. Bogdanski P, Suliburska J, Szulinska M, Stepien M, Pupek-Musialik D, Jablecka A.Greentea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients.

Nutr Res. 2012 Jun;32(6):421-7. doi: 10.1016/j.nutres.2012.05.007. Epub 2012 Jun 20.

  1. Razavi SM, Gholamin S, Eskandari A, Mohsenian N, Ghorbanihaghjo A, Delazar A, Rashtchizadeh N, Keshtkar-Jahromi M, Argani H. Redgrape seed extract improves lipid profiles and decreases oxidized low-density lipoprotein in patients with mild hyperlipidemia.

J Med Food. 2013 Mar;16(3):255-8. doi: 10.1089/jmf.2012.2408. Epub 2013 Feb 25.

  1. De Groote D, Van Belleghem K, Devière J, Van Brussel W, Mukaneza A, Amininejad L. Effect of the intake of resveratrol, resveratrol phosphate, and catechin-richgrape seed extract on markers of oxidative stress and gene expression in adult obese subjects.

Ann Nutr Metab. 2012;61(1):15-24. doi: 10.1159/000338634. Epub 2012 Jul 5.

  1. Sano A, Tokutake S, Seo A. Proanthocyanidin-richgrape seed extract reduces leg swelling in healthy women during prolonged sitting.

J Sci Food Agric. 2013 Feb;93(3):457-62. doi: 10.1002/jsfa.5773. Epub 2012 Jul 2.

  1. Kar P, Laight D, Rooprai HK, Shaw KM, Cummings M. Effects ofgrape seed extract in Type 2 diabetic subjects at high cardiovascular risk: a double blind randomized placebo controlled trial examining metabolic markers, vascular tone, inflammation, oxidative stress and insulin sensitivity. Diabet Med. 2009 May;26(5):526-31. doi: 10.1111/j.1464-5491.2009.02727.x.
  2. Yubero N, Sanz-Buenhombre M, Guadarrama A, Villanueva S, Carrión JM, Larrarte E, Moro C. LDL cholesterol-lowering effects of grape extract used as a dietary supplement on healthy volunteers. Int J Food Sci Nutr. 2013 Jun;64(4):400-6. doi: 10.3109/09637486.2012.753040. Epub 2012 Dec 19.